Protocol Library
Peptide protocols, graded by evidence
A protocol reference for research compounds — mechanism, dosing where a real trial established one, reconstitution math, storage and sourcing. Every page carries an evidence badge, because the most useful thing we can tell you about most of these compounds is how much is actually known.
How to read these pages
- 26 compounds have human trial data. Their pages carry the schedule that was actually administered, with the citation.
- 23 have animal data only. Their pages explain what the preclinical work showed and why no human schedule can be cited.
- 11 have no meaningful dosing literature. We say so rather than print a number.
Why we do it this way. It would be easy to publish a confident schedule for every compound here — plenty of sites do. But most research peptides have never been dosed in a human trial, and a table that looks identical for a phase 3 drug and for a compound only ever given to rats is actively misleading. The badge tells you which one you are reading in about a second.
GLP-1 & Metabolic
Semaglutide Human trial data
A GLP-1 receptor agonist carrying a fatty-acid chain that binds albumin and stretches its half-life to about a week. It slows gastric emptying, increa…
Tirzepatide Human trial data
A single peptide that activates both the GIP and GLP-1 receptors. That dual mechanism is what separates it from semaglutide and is the leading explana…
Retatrutide Human trial data
Adds glucagon-receptor agonism to the GIP/GLP-1 combination. Glucagon activity is thought to raise energy expenditure directly, which is the proposed …
Cagrilintide Human trial data
A long-acting analog of amylin, a pancreatic hormone co-secreted with insulin. It acts on satiety pathways distinct from GLP-1, which is why it is stu…
CagriSema Human trial data
A fixed combination of an amylin analog and a GLP-1 agonist. The rationale is that the two act on separate satiety pathways, so the combination is stu…
AOD-9604 Human trial data
The C-terminal fragment of human growth hormone, developed on the hypothesis that the lipolytic activity of hGH could be separated from its growth-pro…
5-Amino-1MQ Animal data only
A small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT). Inhibiting NNMT raises intracellular NAD+ and has reduced adipocyte size in rod…
SLU-PP-332 Animal data only
A pan-agonist of the estrogen-related receptors (ERRα/β/γ), studied as an "exercise mimetic" for its effects on oxidative metabolism and mitochondrial…
L-Carnitine Human trial data
Transports long-chain fatty acids across the inner mitochondrial membrane for beta-oxidation. Levocarnitine is an approved drug for primary and second…
LIPO-C No dosing literature
A compounded combination of lipotropic agents — commonly methionine, inositol and choline, sometimes with B-vitamins. It is a formulation category rat…
Healing & Repair
BPC-157 Animal data only
A synthetic pentadecapeptide derived from a sequence found in human gastric juice. Rodent work reports accelerated tendon, muscle and gut healing, wit…
TB-500 Animal data only
A synthetic fragment of thymosin beta-4, the actin-sequestering protein. The parent protein has been studied in human trials for wound healing and dry…
BPC-157 + TB-500 Blend Animal data only
A fixed-ratio combination of the two most-discussed repair peptides, sold in one vial so a single draw delivers both. The pairing rationale is that th…
KPV Animal data only
The C-terminal tripeptide of alpha-MSH. It carries the anti-inflammatory activity of the parent hormone without the pigmentation effects, and acts par…
GLOW Blend Animal data only
A three-component repair blend combining the two most-discussed repair peptides with the copper tripeptide. Sold as one vial, so a single draw deliver…
KLOW Blend Animal data only
GLOW with KPV added as a fourth component, on the rationale that KPV contributes an anti-inflammatory mechanism the other three do not.
LL-37 Animal data only
The only human cathelicidin-derived antimicrobial peptide. It has direct antimicrobial activity and a broad immunomodulatory role, and is studied in w…
ARA-290 Human trial data
An 11-amino-acid peptide derived from the helix-B domain of erythropoietin. It engages the innate repair receptor without the erythropoietic activity …
PE-22-28 Animal data only
A shortened analog of spadin, which blocks the TREK-1 potassium channel. Rodent work studies it for rapid antidepressant-like effects and for synaptog…
Growth Hormone Axis
Sermorelin Human trial data
The first 29 amino acids of growth-hormone-releasing hormone, which is the shortest fragment retaining full activity. It stimulates the pituitary to r…
Ipamorelin Human trial data
A pentapeptide agonist at the ghrelin receptor (GHS-R1a). Its selling point in the literature is selectivity — unlike earlier secretagogues it release…
Tesamorelin Human trial data
A GHRH analog with a trans-3-hexenoyl group added to the N-terminus, which protects it from degradation by dipeptidyl peptidase-4 and extends its acti…
CJC-1295 with DAC Human trial data
A GHRH analog carrying a Drug Affinity Complex — a maleimide group that binds covalently to serum albumin after injection. That bond is what stretches…
CJC-1295 + Ipamorelin Animal data only
Pairs a GHRH analog with a ghrelin-receptor agonist. The rationale is that the two act on different receptors, so the combination is expected to produ…
Tesamorelin + Ipamorelin Animal data only
Combines an approved GHRH analog with a ghrelin-receptor agonist in one vial, on the same two-receptor rationale as the CJC/ipamorelin pairing but usi…
IGF-1 LR3 Animal data only
An IGF-1 analog with an arginine substitution at position 3 and a 13-amino-acid N-terminal extension. Those changes sharply reduce binding to IGF bind…
GHRP-2 Human trial data
A synthetic hexapeptide agonist at the ghrelin receptor. It is a more potent GH releaser than GHRP-6 with less appetite stimulation, and unlike most c…
GHRP-6 Human trial data
The earliest of the growth-hormone-releasing hexapeptides and the compound that led to the discovery of the ghrelin receptor. It is a strong GH releas…
PEG-MGF Animal data only
A pegylated form of mechano growth factor, an IGF-1 splice variant expressed by muscle in response to mechanical loading and damage. Pegylation is int…
Follistatin Animal data only
A glycoprotein that binds and neutralises members of the TGF-beta family including activin A and myostatin. Blocking myostatin removes a brake on musc…
Cognitive & Neuro
Semax Human trial data
A synthetic analog of the ACTH 4-10 fragment with a Pro-Gly-Pro tail that resists enzymatic breakdown. It has no corticotropic activity — the adrenal-…
Selank Human trial data
A synthetic analog of the immunopeptide tuftsin, again with a Pro-Gly-Pro tail for stability. It is studied as an anxiolytic without the sedation or d…
Semax + Selank Blend Animal data only
Combines the two Russian-developed regulatory peptides in one vial. They came out of the same research programme and are often discussed together, but…
Cerebrolysin Human trial data
Not a single peptide but a standardised mixture of low-molecular-weight peptides and amino acids produced by enzymatic breakdown of purified porcine b…
DSIP Animal data only
A nonapeptide originally isolated from the cerebral venous blood of rabbits in induced sleep, and named for the delta-wave activity observed. Its endo…
Dihexa Animal data only
A small angiotensin IV analog developed to be orally active and blood-brain-barrier penetrant. It is reported to potentiate hepatocyte growth factor s…
Adamax No dosing literature
Marketed as a nootropic peptide related to the Semax family. Independent characterisation of its structure and pharmacology in the peer-reviewed liter…
Longevity & Cellular
SS-31 Human trial data
A cell-permeable tetrapeptide that concentrates selectively at the inner mitochondrial membrane, where it associates with cardiolipin. Stabilising car…
NAD+ Human trial data
A coenzyme central to redox reactions and a substrate for sirtuins and PARPs. Tissue NAD+ falls with age, which is the basis of interest in restoring …
Glutathione Human trial data
The body’s principal intracellular antioxidant, a tripeptide of glutamate, cysteine and glycine. Oral glutathione is largely broken down before absorp…
MOTS-c Animal data only
A 16-amino-acid peptide encoded in mitochondrial DNA rather than the nuclear genome — one of a small group of mitochondrial-derived peptides. Rodent w…
Epitalon Human trial data
A synthetic tetrapeptide developed as a simplified version of Epithalamin, a pineal-gland extract. It is studied for effects on telomerase expression …
FOXO4-DRI Animal data only
A D-retro-inverso peptide designed to disrupt the interaction between FOXO4 and p53 in senescent cells, pushing those cells into apoptosis while spari…
Cartalax No dosing literature
A short synthetic peptide from the Khavinson bioregulator series, associated in that literature with cartilage and connective tissue.
Pinealon No dosing literature
A tripeptide from the same Khavinson bioregulator series, associated in that literature with brain tissue and studied in rodent models of hypoxia and …
Cortagen No dosing literature
A Khavinson-series peptide associated with cerebral cortex tissue in that literature.
Vesugen No dosing literature
A Khavinson-series tripeptide associated with vascular tissue in that literature.
Ovagen No dosing literature
A Khavinson-series peptide associated with liver and ovarian tissue in that literature.
Prostamax No dosing literature
A Khavinson-series peptide associated with prostate tissue in that literature.
Testagen No dosing literature
A Khavinson-series peptide associated with testicular tissue in that literature.
Immune & Thymic
Thymosin Alpha-1 Human trial data
A 28-amino-acid peptide originally isolated from thymic tissue. It acts on Toll-like receptors and promotes T-cell maturation and dendritic-cell funct…
Thymalin No dosing literature
A polypeptide complex extracted from calf thymus, rather than a single defined peptide. It sits in the same Russian bioregulator tradition as the Khav…
Sexual & Cosmetic
PT-141 Human trial data
A melanocortin-receptor agonist derived from the alpha-MSH analog melanotan II. It acts centrally on MC4 receptors rather than on the vascular system,…
Melanotan I Human trial data
A linear analog of alpha-melanocyte-stimulating hormone that acts principally at MC1 receptors, driving eumelanin production. The approved product is …
Melanotan II Animal data only
A cyclic, non-selective melanocortin agonist. Unlike Melanotan I it hits MC1, MC3, MC4 and MC5 — the MC4 activity is why it produces sexual and appeti…
Kisspeptin-10 Human trial data
The product of the KISS1 gene and the upstream trigger of the reproductive axis: it stimulates GnRH release from the hypothalamus, which drives LH and…
Oxytocin Human trial data
A nine-amino-acid hypothalamic hormone acting on uterine smooth muscle and mammary myoepithelium, and centrally on social and affiliative behaviour. I…
GHK-Cu Animal data only
A naturally occurring tripeptide (glycyl-histidyl-lysine) that binds copper with high affinity. The copper complex is the active form, and it is studi…
SNAP-8 No dosing literature
An eight-amino-acid extension of the peptide Argireline, designed to interfere with SNARE-complex formation and so reduce the muscle contraction under…
Advanced & Experimental
PNC-27 Animal data only
A peptide combining a p53-derived segment with a membrane-penetrating sequence. In cell culture it is reported to bind HDM-2 in the membrane of cancer…
For laboratory research use only. These pages document published literature. They are not recommendations, treatment plans, or medical advice. Compounds referenced are sold strictly as research chemicals and are not for human or veterinary use. Some supplier links are affiliate links and may earn us a commission.
