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Protocol Reference
Animal data only

GHK-Cu protocol

GHK-Cu (copper tripeptide-1). The published work on this compound is animal or cell-culture research. No human dosing schedule exists to cite.

Category
Sexual & Cosmetic
Common vials
50, 100 mg
Half-life
Short systemically
Route in the literature
Topical in the human literature
Evidence level
Animal data only

How GHK-Cu works

A naturally occurring tripeptide (glycyl-histidyl-lysine) that binds copper with high affinity. The copper complex is the active form, and it is studied for effects on collagen synthesis, wound repair and antioxidant enzyme expression.

GHK-Cu dosing — what the literature actually supports

Animal data only. GHK-Cu has genuine human evidence — but it is topical and cosmetic, from creams and post-procedure skin studies where the relevant figure is a percentage concentration in a formulation, not an injected amount. There is no human trial of injected GHK-Cu establishing a schedule. A percentage in a cream cannot be converted into a subcutaneous dose, and the copper content is an additional reason not to improvise systemic amounts.

We publish a schedule when there is a citable human source and we say so when there is not. Filling this space with a number nobody measured would make the page look more complete and be worth less than nothing to you.

Reconstitution and measurement

This part is arithmetic and does not depend on the evidence level. Concentration is vial size divided by the bacteriostatic water you add. Draw volume is your target amount divided by that concentration. Units are draw volume times 100, because a U-100 syringe reads 100 units per millilitre. Common vials for GHK-Cu: 50, 100 mg.

Open the GHK-Cu calculator → Unit converter

Storage and stability

Dry powder
Cold, dark and dry. Lyophilized peptide is the stable form — keep it that way until you intend to use it.
After reconstitution
Refrigerate at 2–8 °C, protect from light, and plan around a limited window. Do not freeze a reconstituted vial — freeze-thaw damages peptides.
Mixing
Run bacteriostatic water down the inside wall of the vial rather than onto the powder, then swirl. Never shake.
Inspect before use
A clear solution is expected. Cloudiness or particles mean discard, not use.

Full storage guide → · Cloudy solution?

Reported effects

  • No human safety data for injected GHK-Cu.
  • Topical use is well tolerated in the cosmetic literature.
  • Because it is a copper complex, systemic copper load is a real consideration that does not arise with topical use.

Sourcing GHK-Cu

Whatever you are working with, the documentation matters more than the price. Ask for a batch certificate of analysis whose lot number matches the vial you actually receive — a COA for a different batch tells you nothing about yours.

GHK-Cu at Summit Research Supply → Grade a COA first

Summit is the supplier we feature and an affiliate link. Our COA checklist applies the same way to any vendor.

For laboratory research use only. This page documents what the published literature reports about GHK-Cu. It is not a recommendation, not a treatment plan, and not medical advice. Compounds referenced are sold strictly as research chemicals and are not for human or veterinary use. Some supplier links are affiliate links and may earn us a commission. This never affects tier placement or review conclusions.
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