Thymosin Alpha-1 protocol
Thymosin Alpha-1 (thymalfasin). Dosing on this page comes from a published human trial or an approved product label, cited below.
How Thymosin Alpha-1 works
A 28-amino-acid peptide originally isolated from thymic tissue. It acts on Toll-like receptors and promotes T-cell maturation and dendritic-cell function, which is why it is studied as an immune modulator rather than a stimulant.
Thymosin Alpha-1 dosing schedule
From the approved label. Thymalfasin is marketed as Zadaxin and approved in around thirty countries for chronic hepatitis B and as a vaccine adjuvant, though it is not FDA-approved in the United States. This is one of the few compounds in this category with a real regulatory dossier behind it.
| Phase | Amount | Frequency | Notes |
|---|---|---|---|
| Approved use | 1.6 mg | Twice weekly, subcutaneous | The labelled amount and frequency for chronic hepatitis B. |
Study length: Six months in the chronic hepatitis B indication.
Reconstitution and measurement
This part is arithmetic and does not depend on the evidence level. Concentration is vial size divided by the bacteriostatic water you add. Draw volume is your target amount divided by that concentration. Units are draw volume times 100, because a U-100 syringe reads 100 units per millilitre. Common vials for Thymosin Alpha-1: 10 mg.
Storage and stability
Reported effects
- The label describes it as well tolerated, with injection-site discomfort the most common complaint.
- Because it modulates rather than broadly stimulates immune function, it has also been studied in sepsis and in oncology adjunct settings.
- Not FDA-approved in the United States, which is worth knowing given how it is often described.
Sourcing Thymosin Alpha-1
Whatever you are working with, the documentation matters more than the price. Ask for a batch certificate of analysis whose lot number matches the vial you actually receive — a COA for a different batch tells you nothing about yours.
Thymosin Alpha-1 at Summit Research Supply → Grade a COA first
Summit is the supplier we feature and an affiliate link. Our COA checklist applies the same way to any vendor.
