CJC-1295 with DAC protocol
CJC-1295 with DAC (long-acting GHRH analog). Dosing on this page comes from a published human trial or an approved product label, cited below.
How CJC-1295 with DAC works
A GHRH analog carrying a Drug Affinity Complex — a maleimide group that binds covalently to serum albumin after injection. That bond is what stretches the half-life from minutes to days, and it is the entire difference between this and the no-DAC version.
CJC-1295 with DAC dosing schedule
From the phase 1 ascending-dose programme in healthy adults — two randomized, double-blind, placebo-controlled trials enrolling 65 subjects between them. This is dose-ranging pharmacology, not an efficacy protocol for any indication.
| Phase | Amount | Frequency | Notes |
|---|---|---|---|
| Ascending single doses | 1, 2, 4, 8, 15, 30 mcg/kg | Single subcutaneous dose | The ascending-dose arms of the phase 1 programme. |
| Higher single doses | 30, 60, 90 mcg/kg | Single subcutaneous dose | Produced 2–10 fold increases in mean plasma GH for 6+ days and 1.5–3 fold IGF-1 increases lasting 9–11 days. |
| Repeat dosing | Weekly or biweekly | 2–3 doses | The second trial in the programme tested multiple dosing. |
Study length: Single doses in the first trial; two or three weekly or biweekly doses in the second.
Reconstitution and measurement
This part is arithmetic and does not depend on the evidence level. Concentration is vial size divided by the bacteriostatic water you add. Draw volume is your target amount divided by that concentration. Units are draw volume times 100, because a U-100 syringe reads 100 units per millilitre. Common vials for CJC-1295 with DAC: 5 mg.
Storage and stability
Reported effects
- The phase 1 programme reported the compound as generally well tolerated at the amounts studied.
- The long duration of IGF-1 elevation — 9 to 11 days from a single dose — is the defining pharmacological feature and the reason weekly dosing is even plausible.
- No approved label exists for any indication.
Sourcing CJC-1295 with DAC
Whatever you are working with, the documentation matters more than the price. Ask for a batch certificate of analysis whose lot number matches the vial you actually receive — a COA for a different batch tells you nothing about yours.
CJC-1295 with DAC at Summit Research Supply → Grade a COA first
Summit is the supplier we feature and an affiliate link. Our COA checklist applies the same way to any vendor.
