Protocol Reference
Animal data only
LL-37 protocol
LL-37 (human cathelicidin antimicrobial peptide). The published work on this compound is animal or cell-culture research. No human dosing schedule exists to cite.
PepGuru Research Team·Reviewed Aug 2026
Common vials
Not stocked by our featured supplier
Route in the literature
Not established for systemic use
Evidence level
Animal data only
How LL-37 works
The only human cathelicidin-derived antimicrobial peptide. It has direct antimicrobial activity and a broad immunomodulatory role, and is studied in wound healing and infection.
LL-37 dosing — what the literature actually supports
Animal data only. Human work with LL-37 has been largely topical and in a wound-healing context; there is no established systemic injected schedule. LL-37 is also cytotoxic to host cells above certain concentrations, which is a specific reason not to extrapolate an amount from in-vitro work.
We publish a schedule when there is a citable human source and we say so when there is not. Filling this space with a number nobody measured would make the page look more complete and be worth less than nothing to you.
Reconstitution and measurement
This part is arithmetic and does not depend on the evidence level. Concentration is vial size divided by the bacteriostatic water you add. Draw volume is your target amount divided by that concentration. Units are draw volume times 100, because a U-100 syringe reads 100 units per millilitre. Common vials for LL-37: Not stocked by our featured supplier.
Open the LL-37 calculator → Unit converter
Storage and stability
Dry powder
Cold, dark and dry. Lyophilized peptide is the stable form — keep it that way until you intend to use it.
After reconstitution
Refrigerate at 2–8 °C, protect from light, and plan around a limited window. Do not freeze a reconstituted vial — freeze-thaw damages peptides.
Mixing
Run bacteriostatic water down the inside wall of the vial rather than onto the powder, then swirl. Never shake.
Inspect before use
A clear solution is expected. Cloudiness or particles mean discard, not use.
Full storage guide → · Cloudy solution?
Reported effects
- No established systemic human safety profile.
- In-vitro work shows host-cell toxicity above a concentration threshold, so more is explicitly not better with this peptide.
Sourcing LL-37
Our featured supplier does not stock this compound, and we are not going to point you at a vendor we have not looked at. Use the COA checklist on whoever you do buy from, and check the batch number on the certificate against the vial you receive.
COA checklist → How we vet suppliers
Sources and further reading
For laboratory research use only. This page documents what the published literature reports about LL-37. It is not a recommendation, not a treatment plan, and not medical advice. Compounds referenced are sold strictly as research chemicals and are not for human or veterinary use. Some supplier links are affiliate links and may earn us a commission. This never affects tier placement or review conclusions.
