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Reconstitution + Units

Melanotan I Reconstitution & Dosage Calculator

This free Melanotan I calculator turns your vial size, the bacteriostatic water you add, and your target amount into a concentration, a draw volume, and the exact units on a U-100 insulin syringe. Melanotan I is the linear alpha-MSH analog — the same molecule approved as afamelanotide, though the approved product is a slow-release implant rather than a reconstituted injection.

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Melanotan I reconstitution calculator

Step 1

Syringe

U-100 insulin
Step 2

Peptide in vial

Step 3

Target amount

Step 4

Bacteriostatic water

Volume to draw
Concentration
Draw volume
Doses / vial

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Quick summary

  • Converts vial size (mg), bacteriostatic water (mL), and a microgram amount into concentration, draw volume, and U-100 units.
  • Reference math for the 10 mg vial size.
  • Educational research and measurement tool only — it does not diagnose, treat, or recommend an amount.
Compound
Melanotan I / afamelanotide (linear alpha-MSH analog)
Tool type
Reconstitution + unit calculator
Common research vials
10 mg
A common mix
10 mg + 2 mL = 5 mg/mL
Regulatory status
Approved as afamelanotide (implant) for erythropoietic protoporphyria; research powder is not that product

What this Melanotan I calculator does

This calculator does one job well: it turns your vial size, the amount of bacteriostatic water you add, and your target amount into a concentration (mg/mL), a draw volume (mL), and the matching units on a U-100 insulin syringe. Change any input and the result updates instantly.

Melanotan I ships as a freeze-dried powder. Before it can be measured into a syringe it has to be reconstituted — dissolved in bacteriostatic water. How much water you add sets the concentration, and the concentration sets how many units each amount works out to. The presets above cover the most common Melanotan I vial setups; use the custom fields for anything else.

Research-use only — not medical advice. This page and calculator are educational measurement and research-planning tools. They do not recommend an amount, diagnose, or treat anything. Products referenced are sold strictly as research chemicals and are not for human or veterinary use.

How to use the Melanotan I calculator

Pick your syringe

Choose the U-100 insulin syringe you'll draw with. Smaller syringes (0.3 mL / 30u) have finer lines, which helps when the draw is small.

Enter your vial and water

Set the milligrams in your Melanotan I vial and the bacteriostatic water you added. Together these set the concentration.

Set your target amount

Toggle mg or mcg and pick (or type) the amount you're measuring for. The calculator does the conversion for you.

Read the draw

The result panel shows concentration, draw volume, and the exact U-100 units to pull, plus how many doses your vial contains.

Melanotan I reconstitution math, explained

The math is short. Concentration = vial size ÷ bacteriostatic water. Draw volume = target amount ÷ concentration. Units = draw volume × 100 (a U-100 syringe reads 100 units per mL). The table below shows common Melanotan I setups and the units for a 1 mg amount at each.

Vial sizeBac waterConcentrationUnits per 1 mg
10 mg1.0 mL10 mg/mL10 units
10 mg2.0 mL5 mg/mL20 units
10 mg2.5 mL4 mg/mL25 units
10 mg5.0 mL2 mg/mL50 units

Melanotan I amount-to-units reference

How common amounts convert to U-100 syringe units at two example concentrations. These are arithmetic conversions for reference, not a recommendation of any amount.

Units at 5 mg/mL (10 mg + 2 mL)
AmountVolume (mL)U-100 units
250 mcg (0.25 mg)0.05 mL5 units
500 mcg (0.5 mg)0.1 mL10 units
1000 mcg (1 mg)0.2 mL20 units
Units at 2 mg/mL (10 mg + 5 mL)
AmountVolume (mL)U-100 units
250 mcg (0.25 mg)0.125 mL12.5 units
500 mcg (0.5 mg)0.25 mL25 units
1000 mcg (1 mg)0.5 mL50 units

Mixing, color & storage tips

The approved product is an implant

Afamelanotide is licensed as a controlled-release implant placed by a clinician, not as a reconstituted injection. The labelled 16 mg implant figure describes a two-month release profile and does not translate into an injected amount — do not treat the two as comparable.

Melanotan I versus Melanotan II

Melanotan I is linear and acts principally at MC1, which is the pigmentation receptor. Melanotan II is cyclic and non-selective, which is why it also produces appetite and sexual effects. They are different compounds with different profiles.

Mixing without foam

Add the water slowly against the inside wall and swirl gently until clear. Do not shake.

Storage and skin monitoring

Refrigerate once reconstituted and keep it dark. Melanocortin agonists can affect the appearance of existing moles, and the approved product's label calls for skin monitoring for that reason.

Melanotan I supplies checklist

A simple reconstitution shopping list. Confirm vial size and batch documentation before you buy.

Melanotan I research vial
COA-verified, third-party tested
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Bacteriostatic water
0.9% benzyl alcohol, for reconstitution
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U-100 insulin syringes
0.3–1.0 mL, for accurate small draws
Any pharmacy
Alcohol prep pads
Sterilize the stopper before each draw
Any pharmacy
Verified USA Supplier
Melanotan I research vial
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Melanotan I

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Melanotan I — frequently asked questions

What does this Melanotan I calculator tell me?

It converts your vial size, bacteriostatic water volume, and target amount into concentration in mg/mL, draw volume in mL, and U-100 syringe units. It is a measurement tool, not a recommendation.

Is the Melanotan I calculator free?

Yes — free, browser-based, and no account is required.

Is Melanotan I the same as afamelanotide?

Chemically yes, but the approved medicine is a slow-release subcutaneous implant placed by a healthcare professional, not a reconstituted powder. The delivery method is a substantial difference.

How many units is 500 mcg of Melanotan I?

At 5 mg/mL it is 10 units (0.1 mL). At 2 mg/mL it is 25 units. Units always depend on your exact concentration.

Is this medical advice?

No. This page and calculator are for education and research planning only. Products referenced are sold strictly as research chemicals and are not for human or veterinary use.

Melanotan I protocol & evidence

Dosing for Melanotan I comes from published human trials. The protocol page carries the schedule that was actually administered, with the citation.

Read the Melanotan I protocol page → All protocols

For laboratory research use only. PepGuru is an educational tool for measurement, dilution, and reference. Melanotan I and other compounds referenced are sold strictly as research chemicals and are not for human or veterinary use, not drugs, and not intended to diagnose, treat, cure, or prevent any disease. Nothing here is medical advice. Some supplier links are affiliate links and may earn us a commission. This never affects tier placement or review conclusions.
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