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Protocol Reference
Animal data only

KPV protocol

KPV (Lys-Pro-Val). The published work on this compound is animal or cell-culture research. No human dosing schedule exists to cite.

Category
Healing & Repair
Common vials
10 mg
Half-life
Not established in humans
Route in the literature
Subcutaneous, oral or topical in study work
Evidence level
Animal data only

How KPV works

The C-terminal tripeptide of alpha-MSH. It carries the anti-inflammatory activity of the parent hormone without the pigmentation effects, and acts partly inside the cell on NF-κB signalling.

KPV dosing — what the literature actually supports

Animal data only. KPV has a reasonable preclinical literature in colitis and inflammation models, but no published human trial establishing an injected schedule. The animal work uses oral, topical and intraperitoneal routes at amounts expressed per kilogram of rodent.

We publish a schedule when there is a citable human source and we say so when there is not. Filling this space with a number nobody measured would make the page look more complete and be worth less than nothing to you.

Reconstitution and measurement

This part is arithmetic and does not depend on the evidence level. Concentration is vial size divided by the bacteriostatic water you add. Draw volume is your target amount divided by that concentration. Units are draw volume times 100, because a U-100 syringe reads 100 units per millilitre. Common vials for KPV: 10 mg.

Open the KPV calculator → Unit converter

Storage and stability

Dry powder
Cold, dark and dry. Lyophilized peptide is the stable form — keep it that way until you intend to use it.
After reconstitution
Refrigerate at 2–8 °C, protect from light, and plan around a limited window. Do not freeze a reconstituted vial — freeze-thaw damages peptides.
Mixing
Run bacteriostatic water down the inside wall of the vial rather than onto the powder, then swirl. Never shake.
Inspect before use
A clear solution is expected. Cloudiness or particles mean discard, not use.

Full storage guide → · Cloudy solution?

Reported effects

  • No human safety data from controlled trials.
  • Rodent inflammation models report benefit at low amounts with little observed toxicity.

Sourcing KPV

Whatever you are working with, the documentation matters more than the price. Ask for a batch certificate of analysis whose lot number matches the vial you actually receive — a COA for a different batch tells you nothing about yours.

KPV at Summit Research Supply → Grade a COA first

Summit is the supplier we feature and an affiliate link. Our COA checklist applies the same way to any vendor.

Sources and further reading

For laboratory research use only. This page documents what the published literature reports about KPV. It is not a recommendation, not a treatment plan, and not medical advice. Compounds referenced are sold strictly as research chemicals and are not for human or veterinary use. Some supplier links are affiliate links and may earn us a commission. This never affects tier placement or review conclusions.
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