The Longevity Lineup
Mitochondria, NAD+ and the telomere peptide: the cellular-health rotation.
Why this stack
Longevity stacks rotate rather than run flat. NAD+ and MOTS-c support cellular energy and metabolic signalling on an ongoing basis, SS-31 targets the mitochondrial membrane directly, and epitalon drops in as a short fixed-day course a few times a year rather than a daily habit. None of this is a proven human-outcome protocol, and the evidence badges on each page do the grading.
The protocol at a glance
Community-reported maintenance amounts, derived live from each compound's protocol page. Click through for titration phases, reconstitution steps and the evidence grading behind every number.
Daily drivers
| Compound | Dose | Frequency | Recon | Units/injection |
|---|---|---|---|---|
| NAD+ Human trial data |
100 mg | Once daily | 500 mg + 3 mL | 60 units (0.6 mL) |
| MOTS-c Animal data only |
1 mg | Once daily | 10 mg + 1 mL | 10 units (0.1 mL) |
| SS-31 Human trial data |
10 mg | Once daily | 10 mg + 1 mL | 100 units (1.0 mL) |
Cycled course
| Compound | Dose | Frequency | Recon | Units/injection |
|---|---|---|---|---|
| Epitalon Human trial data |
5 mg | Once daily, evening | 10 mg + 1 mL | 50 units (0.5 mL) |
How it is run
- NAD+ injections are higher volume and commonly split or slowed; flushing is expected.
- MOTS-c pairs with training days in most community protocols.
- Epitalon runs as a short course with months off between rounds.
What the components report
Reported upsides
- NAD+: Essential coenzyme for cellular energy metabolism
- NAD+: Supports DNA repair and sirtuin activation
- MOTS-c: Mitochondrial-derived peptide
- MOTS-c: Exercise mimetic properties in research
- SS-31: Mitochondrial-targeted antioxidant (elamipretide)
- SS-31: Reduces oxidative stress at the mitochondrial membrane
- Epitalon: Telomerase activator in research models
- Epitalon: May support telomere length maintenance
Cautions
- NAD+: Injection site pain and flushing (common)
- NAD+: Nausea with larger doses
- MOTS-c: Injection site reactions
- MOTS-c: Limited human safety data
- SS-31: Injection site reactions
- SS-31: Generally well tolerated in clinical trials
- Epitalon: Injection site reactions
- Epitalon: Generally well tolerated in reported use
Pulled from each compound's benefits and side effects section. Individual responses vary. Not medical advice.
Track this stack
The free tracker logs each component on its own schedule, rotates injection sites across the whole stack, and counts down every vial with a reorder heads-up.
Sourcing the stack
Same rule as every protocol page: the batch COA matters more than the price. Summit Research Supply is the supplier we feature; code PEPDOSE applies to each component.
NAD+ →MOTS-c →SS-31 →Epitalon →
Summit links are affiliate links. Our COA checklist applies the same way to any vendor.
