Epitalon protocol
Epitalon / Epithalon (Ala-Glu-Asp-Gly). Dosing on this page comes from a published human trial or an approved product label, cited below.
How Epitalon works
A synthetic tetrapeptide developed as a simplified version of Epithalamin, a pineal-gland extract. It is studied for effects on telomerase expression and circadian regulation.
Epitalon dosing schedule
Human data comes almost entirely from the Khavinson group in St Petersburg, including long-running geriatric cohort work with Epithalamin and later Epitalon. This needs stating plainly: the body of evidence originates from essentially one research group, has had little independent replication outside Russia, and the older studies do not meet current trial-reporting standards. The course structure below is what that literature describes.
| Phase | Amount | Frequency | Notes |
|---|---|---|---|
| Reported course | 10 mg per administration | Daily or alternate days across a ~10-day course | As described in the published Russian course-based work. Treat as a reported course structure, not a validated protocol. |
Study length: Short courses of about 10 days, repeated periodically rather than dosed continuously — the defining feature of this literature’s approach.
Reconstitution and measurement
This part is arithmetic and does not depend on the evidence level. Concentration is vial size divided by the bacteriostatic water you add. Draw volume is your target amount divided by that concentration. Units are draw volume times 100, because a U-100 syringe reads 100 units per millilitre. Common vials for Epitalon: 10 mg.
Storage and stability
Reported effects
- The published Russian work reports good tolerability across long follow-up.
- The central weakness is provenance, not a specific safety signal: near-total absence of independent replication.
- Telomerase-related claims come from cell-culture work and should not be read as demonstrated human outcomes.
Sourcing Epitalon
Whatever you are working with, the documentation matters more than the price. Ask for a batch certificate of analysis whose lot number matches the vial you actually receive — a COA for a different batch tells you nothing about yours.
Epitalon at Summit Research Supply → Grade a COA first
Summit is the supplier we feature and an affiliate link. Our COA checklist applies the same way to any vendor.
