Melanotan I Reconstitution & Dosage Calculator
This free Melanotan I calculator turns your vial size, the bacteriostatic water you add, and your target amount into a concentration, a draw volume, and the exact units on a U-100 insulin syringe. Melanotan I is the linear alpha-MSH analog — the same molecule approved as afamelanotide, though the approved product is a slow-release implant rather than a reconstituted injection.
Melanotan I reconstitution calculator
Syringe
U-100 insulinPeptide in vial
Target amount
Bacteriostatic water
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Quick summary
- Converts vial size (mg), bacteriostatic water (mL), and a microgram amount into concentration, draw volume, and U-100 units.
- Reference math for the 10 mg vial size.
- Educational research and measurement tool only — it does not diagnose, treat, or recommend an amount.
What this Melanotan I calculator does
This calculator does one job well: it turns your vial size, the amount of bacteriostatic water you add, and your target amount into a concentration (mg/mL), a draw volume (mL), and the matching units on a U-100 insulin syringe. Change any input and the result updates instantly.
Melanotan I ships as a freeze-dried powder. Before it can be measured into a syringe it has to be reconstituted — dissolved in bacteriostatic water. How much water you add sets the concentration, and the concentration sets how many units each amount works out to. The presets above cover the most common Melanotan I vial setups; use the custom fields for anything else.
How to use the Melanotan I calculator
Pick your syringe
Choose the U-100 insulin syringe you'll draw with. Smaller syringes (0.3 mL / 30u) have finer lines, which helps when the draw is small.
Enter your vial and water
Set the milligrams in your Melanotan I vial and the bacteriostatic water you added. Together these set the concentration.
Set your target amount
Toggle mg or mcg and pick (or type) the amount you're measuring for. The calculator does the conversion for you.
Read the draw
The result panel shows concentration, draw volume, and the exact U-100 units to pull, plus how many doses your vial contains.
Melanotan I reconstitution math, explained
The math is short. Concentration = vial size ÷ bacteriostatic water. Draw volume = target amount ÷ concentration. Units = draw volume × 100 (a U-100 syringe reads 100 units per mL). The table below shows common Melanotan I setups and the units for a 1 mg amount at each.
| Vial size | Bac water | Concentration | Units per 1 mg |
|---|---|---|---|
| 10 mg | 1.0 mL | 10 mg/mL | 10 units |
| 10 mg | 2.0 mL | 5 mg/mL | 20 units |
| 10 mg | 2.5 mL | 4 mg/mL | 25 units |
| 10 mg | 5.0 mL | 2 mg/mL | 50 units |
Melanotan I amount-to-units reference
How common amounts convert to U-100 syringe units at two example concentrations. These are arithmetic conversions for reference, not a recommendation of any amount.
| Amount | Volume (mL) | U-100 units |
|---|---|---|
| 250 mcg (0.25 mg) | 0.05 mL | 5 units |
| 500 mcg (0.5 mg) | 0.1 mL | 10 units |
| 1000 mcg (1 mg) | 0.2 mL | 20 units |
| Amount | Volume (mL) | U-100 units |
|---|---|---|
| 250 mcg (0.25 mg) | 0.125 mL | 12.5 units |
| 500 mcg (0.5 mg) | 0.25 mL | 25 units |
| 1000 mcg (1 mg) | 0.5 mL | 50 units |
Mixing, color & storage tips
The approved product is an implant
Afamelanotide is licensed as a controlled-release implant placed by a clinician, not as a reconstituted injection. The labelled 16 mg implant figure describes a two-month release profile and does not translate into an injected amount — do not treat the two as comparable.
Melanotan I versus Melanotan II
Melanotan I is linear and acts principally at MC1, which is the pigmentation receptor. Melanotan II is cyclic and non-selective, which is why it also produces appetite and sexual effects. They are different compounds with different profiles.
Mixing without foam
Add the water slowly against the inside wall and swirl gently until clear. Do not shake.
Storage and skin monitoring
Refrigerate once reconstituted and keep it dark. Melanocortin agonists can affect the appearance of existing moles, and the approved product's label calls for skin monitoring for that reason.
Melanotan I supplies checklist
A simple reconstitution shopping list. Confirm vial size and batch documentation before you buy.

Melanotan I
- Batch COA on every vial
- Third-party purity tested
- U.S. fulfillment, discreet shipping
Melanotan I — frequently asked questions
What does this Melanotan I calculator tell me?
It converts your vial size, bacteriostatic water volume, and target amount into concentration in mg/mL, draw volume in mL, and U-100 syringe units. It is a measurement tool, not a recommendation.
Is the Melanotan I calculator free?
Yes — free, browser-based, and no account is required.
Is Melanotan I the same as afamelanotide?
Chemically yes, but the approved medicine is a slow-release subcutaneous implant placed by a healthcare professional, not a reconstituted powder. The delivery method is a substantial difference.
How many units is 500 mcg of Melanotan I?
At 5 mg/mL it is 10 units (0.1 mL). At 2 mg/mL it is 25 units. Units always depend on your exact concentration.
Is this medical advice?
No. This page and calculator are for education and research planning only. Products referenced are sold strictly as research chemicals and are not for human or veterinary use.
Sources & further reading
Related calculators
Melanotan I protocol & evidence
Dosing for Melanotan I comes from published human trials. The protocol page carries the schedule that was actually administered, with the citation.

