Protocol Reference
Animal data only
DSIP protocol
DSIP (delta sleep-inducing peptide). The published work on this compound is animal or cell-culture research. No human dosing schedule exists to cite.
PepGuru Research Team·Reviewed Aug 2026
Category
Cognitive & Neuro
Half-life
Very short — minutes
Route in the literature
Intravenous in the older study literature
Evidence level
Animal data only
How DSIP works
A nonapeptide originally isolated from the cerebral venous blood of rabbits in induced sleep, and named for the delta-wave activity observed. Its endogenous role in humans has never been firmly established.
DSIP dosing — what the literature actually supports
Animal data only. DSIP has a scattering of small human studies from the late 1970s and 1980s, mostly in chronic insomnia and pain, but they used varied routes and amounts, produced inconsistent results, and were never followed by a programme that established a schedule. There is no modern trial and no citable protocol. Its very short half-life is also poorly matched to any straightforward dosing approach.
We publish a schedule when there is a citable human source and we say so when there is not. Filling this space with a number nobody measured would make the page look more complete and be worth less than nothing to you.
Reconstitution and measurement
This part is arithmetic and does not depend on the evidence level. Concentration is vial size divided by the bacteriostatic water you add. Draw volume is your target amount divided by that concentration. Units are draw volume times 100, because a U-100 syringe reads 100 units per millilitre. Common vials for DSIP: 5 mg.
Open the DSIP calculator → Unit converter
Storage and stability
Dry powder
Cold, dark and dry. Lyophilized peptide is the stable form — keep it that way until you intend to use it.
After reconstitution
Refrigerate at 2–8 °C, protect from light, and plan around a limited window. Do not freeze a reconstituted vial — freeze-thaw damages peptides.
Mixing
Run bacteriostatic water down the inside wall of the vial rather than onto the powder, then swirl. Never shake.
Inspect before use
A clear solution is expected. Cloudiness or particles mean discard, not use.
Full storage guide → · Cloudy solution?
Reported effects
- No modern human safety data.
- The historical studies did not produce consistent sleep-architecture findings, which is part of why development stopped.
Sourcing DSIP
Whatever you are working with, the documentation matters more than the price. Ask for a batch certificate of analysis whose lot number matches the vial you actually receive — a COA for a different batch tells you nothing about yours.
DSIP at Summit Research Supply → Grade a COA first
Summit is the supplier we feature and an affiliate link. Our COA checklist applies the same way to any vendor.
Sources and further reading
For laboratory research use only. This page documents what the published literature reports about DSIP. It is not a recommendation, not a treatment plan, and not medical advice. Compounds referenced are sold strictly as research chemicals and are not for human or veterinary use. Some supplier links are affiliate links and may earn us a commission. This never affects tier placement or review conclusions.
