Cerebrolysin protocol
Cerebrolysin (porcine brain-derived peptide preparation). Dosing on this page comes from a published human trial or an approved product label, cited below.
How Cerebrolysin works
Not a single peptide but a standardised mixture of low-molecular-weight peptides and amino acids produced by enzymatic breakdown of purified porcine brain protein. Its proposed action is neurotrophic, resembling endogenous growth factors.
Cerebrolysin dosing schedule
Cerebrolysin is an approved medicine in a number of countries in Europe and Asia, and has been studied in sizeable stroke, traumatic brain injury and dementia trials. Efficacy remains contested — Cochrane reviews of the stroke evidence have not found convincing benefit — but the dosing itself is well documented.
| Phase | Amount | Frequency | Notes |
|---|---|---|---|
| Acute stroke trials | 30 mL | Once daily, intravenous infusion | A commonly used trial amount, given over a course of consecutive days. |
| Higher trial arms | 50 mL | Once daily, intravenous infusion | Used in some traumatic brain injury and stroke protocols. |
| Lower / maintenance arms | 10 mL | Daily, intramuscular or intravenous | Appears in dementia and milder-indication protocols. |
Study length: Courses of 10–21 consecutive days are the norm across the trial literature.
Reconstitution and measurement
This part is arithmetic and does not depend on the evidence level. Concentration is vial size divided by the bacteriostatic water you add. Draw volume is your target amount divided by that concentration. Units are draw volume times 100, because a U-100 syringe reads 100 units per millilitre. Common vials for Cerebrolysin: Not stocked by our featured supplier.
Storage and stability
Reported effects
- Trial reporting generally describes good tolerability, with dizziness and injection-site effects most commonly noted.
- It is a porcine-derived biological product, so hypersensitivity is a relevant consideration.
- Efficacy is genuinely contested in systematic reviews — a well-documented schedule is not the same as a demonstrated benefit.
Sourcing Cerebrolysin
Our featured supplier does not stock this compound, and we are not going to point you at a vendor we have not looked at. Use the COA checklist on whoever you do buy from, and check the batch number on the certificate against the vial you receive.
